id: Pfam:PF06762
pfam_id: PF06762
name: Lipase maturation factor transmembrane domain
short_name: LMF1
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06762
counters:
  proteins: 4751
  matches: 4909
  proteomes: 2921
  taxa: 6050
  structures: 0
  alphafold_models: 3452
  domain_architectures: 66
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR057434
description: This entry represents a domain found in the transmembrane proteins lipase maturation factor,
  LMF1 and LMF2. Lipoprotein lipase and hepatic lipase require LMF1 to fold into their active states [[cite:PUB00057509]].
  It acts as a chaperone required for maturation and transport of active lipoprotein lipase (LPL), through
  the secretory pathway [[cite:PUB00057511],[cite:PUB00098585]]. This domain is predicted as a transmembrane.
  It contains two structural repeats each of which is similar to members of the DoxD-like superfamily.