id: Pfam:PF06824
pfam_id: PF06824
name: Metal-independent alpha-mannosidase (GH125)
short_name: Glyco_hydro_125
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06824
counters:
  proteins: 5382
  matches: 5479
  proteomes: 3430
  taxa: 5989
  structures: 12
  alphafold_models: 3901
  domain_architectures: 59
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR008313
description: This family, which contains bacterial and fungal glycoside hydrolases, is also known as GH125.
  They function as metal-independent alpha-mannosidases, with specificity for alpha-1,6-linked non-reducing
  terminal mannose residues[[cite:PUB00055745]]. Structurally this family is part of the 6 hairpin glycosidase
  superfamily.