id: Pfam:PF06916
pfam_id: PF06916
name: FAM210A/B-like domain
short_name: FAM210A-B_dom
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06916
counters:
  proteins: 5800
  matches: 5823
  proteomes: 3286
  taxa: 8695
  structures: 0
  alphafold_models: 5002
  domain_architectures: 81
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR009688
description: This domain is found in mitochondrial proteins, including FAM210A and B, which contains a
  transmembrane peptide [[cite:PUB00097753],[cite:PUB00097752],[cite:PUB00097751]]. Its function is not
  clear. FAM210A, a protein essential in maintaining skeletal muscle structure and strength [[cite:PUB00097754]],
  interacts with mitochondrial translation elongation factor EF-Tu and promotes mitochondrial protein
  expression. In FAM210A, this domain is responsible for binding EF-Tu [[cite:PUB00097751]]. FAM210B plays
  a role in erythroid differentiation and is involved in cell proliferation and tumour cell growth suppression
  [[cite:PUB00097753],[cite:PUB00097755]].