id: Pfam:PF06924
pfam_id: PF06924
name: Protein of unknown function (DUF1281)
short_name: DUF1281
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06924
counters:
  proteins: 175
  matches: 175
  proteomes: 119
  taxa: 215
  structures: 1
  alphafold_models: 118
  domain_architectures: 3
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR009694
description: This entry describes a domain of unkown function found generally at the N-terminal of YubA
  and YubB in enterobacteriaceae. This domain is mostly found in Escherichia coli, Salmonella typhimurium
  and Shigella species. YubA and YubB have not been fully functionally characterised. YubB was identified
  as undecaprenyl diphosphate phosphatase (UPPP) due to its association with cell wall synthesis and bacitracin
  resistance when disrupted. YubA was inferred to be a transporter, possibly related to cell wall synthesis,
  based on its predicted membrane protein structure and its genomic association with the UPPP gene. These
  experiments were done using transposon mutagenesis [[cite:PUB00160281]].