id: Pfam:PF07000
pfam_id: PF07000
name: Protein of unknown function (DUF1308)
short_name: DUF1308
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF07000
counters:
  proteins: 2550
  matches: 2576
  proteomes: 2155
  taxa: 6269
  structures: 0
  alphafold_models: 2190
  domain_architectures: 49
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR010733
description: This is a domain of unknown function found on the C-terminal of C7orf25 protein UPF0415.
  The C-terminal domain is homologous to the known PIN-like domains. The PIN-like domain is widespread
  among eukaryotes, including animals, plants, and fungi, but also present in some cyanobacteria, Deinococcus,
  and dsDNA viruses from the Mimiviridae family. The domain retains up to four potential catalytic residues,
  thus, depending on the protein is predicted to be an active or inactive nuclease and in a majority of
  the family members, the PIN-like domain is N-terminally fused with a potentially active PD-(D/E)XK-like
  domain [pfam:PF18474] [[cite:PUB00091006]].