id: Pfam:PF07126
pfam_id: PF07126
name: Cell-division protein ZapC, C-terminal
short_name: ZapC_C
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF07126
counters:
  proteins: 1065
  matches: 1065
  proteomes: 1061
  taxa: 1410
  structures: 2
  alphafold_models: 670
  domain_architectures: 2
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR048372
description: ZapC is one of four FtsZ-binding components of the Z ring in bacteria. Formation of the Z
  ring on the cytoplasmic surface of the membrane is the starting process for assembly of the cell-division
  apparatus. It binds directly to the Z ring, and although it is not essential for absolute cell division
  it contributes to it by enhancing the interactions between the FtsZ protofilaments (or polymers) which
  aggregate to form the ring conformation in the Z ring [[cite:PUB00060666]]. This is the C-terminal domain
  which contains a pocket with a hydrophobic centre surrounded by conserved basic residues, critical for
  FtsZ binding [[cite:PUB00101038],[cite:PUB00101039]].