id: Pfam:PF07381
pfam_id: PF07381
name: EarA-like
short_name: EarA
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF07381
counters:
  proteins: 76
  matches: 76
  proteomes: 57
  taxa: 144
  structures: 0
  alphafold_models: 75
  domain_architectures: 2
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR010863
description: This family includes EarA from Methanococcus maripaludis (MMP1718, [swissprot:Q6LWJ1]) and
  similar sequences from archaea. EarA is a transcriptional activator that directly regulates the fla
  operon, which contains genes involved in archaella formation [[cite:PUB00158985],[cite:PUB00158986]].
  Proteins in this family possess a winged helix DNA -binding domain.