id: Pfam:PF07385
pfam_id: PF07385
name: D-lyxose isomerase
short_name: Lyx_isomer
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF07385
counters:
  proteins: 1432
  matches: 1432
  proteomes: 1296
  taxa: 2278
  structures: 3
  alphafold_models: 919
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR010864
description: Members of this family of sugar isomerases belong to the cupin superfamily and consist of
  group I and II of D-lyxose isomerases [[cite:PUB00103833]]. The enzyme from Cohnella laevoribosii has
  been shown to be specific for D-lyxose, L-ribose, and D-mannose [[cite:PUB00075374]]. E. coli sugar
  isomerase (EcSI) shows a preference for D-lyxose and D-mannose [[cite:PUB00055252]] and its active site
  is highly similar to YdaE from the sigma B regulon of Bacillus subtilis [[cite:PUB00103833]].