id: Pfam:PF07564
pfam_id: PF07564
name: Domain of Unknown Function (DUF1542)
short_name: DUF1542
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF07564
counters:
  proteins: 393
  matches: 2712
  proteomes: 153
  taxa: 310
  structures: 0
  alphafold_models: 112
  domain_architectures: 192
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR011439
description: This domain is found in several cell surface proteins, such as extracellular matrix-binding
  protein ebh [[cite:PUB00014728]]. Some members are involved in antibiotic resistance (e.g [swissprot:Q9RL69]
  and [swissprot:Q9LCJ9]) [[cite:PUB00014727]] and/or cellular adhesion (e.g. [swissprot:Q931R6]) [[cite:PUB00014728]].
  In some proteins it is repeated more than fifteen times, being the most repeated domain in streptococci
  [[cite:PUB00097824]]. This is a predominantly alpha-helical domain that form a long, thin, fibre-like
  structure and it has been proposed to function as a stalk that helps the adhesive non-repeat region
  (NRR) of proteins protrude beyond the cell surface [[cite:PUB00097823],[cite:PUB00065268]].