id: Pfam:PF07591
pfam_id: PF07591
name: Pretoxin HINT domain
short_name: PT-HINT
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF07591
counters:
  proteins: 4593
  matches: 4640
  proteomes: 2065
  taxa: 3206
  structures: 3
  alphafold_models: 1207
  domain_architectures: 1049
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
description: A member of the HINT superfamily of proteases that is usually found N-terminal to the toxin
  module in polymorphic toxin systems. The domain is predicted to function in releasing the toxin domain
  by autoproteolysis [[cite:PUB00057479]].