id: Pfam:PF07798
pfam_id: PF07798
name: Coiled-coil domain-containing protein 90-like
short_name: CCDC90-like
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF07798
counters:
  proteins: 6646
  matches: 6782
  proteomes: 2866
  taxa: 7214
  structures: 1
  alphafold_models: 5610
  domain_architectures: 96
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR024461
description: This entry includes coiled-coil domain-containing proteins 90 (CCDC90) and related proteins.
  CCDC90A is a key regulator of the mitochondrial calcium uniporter (MCU) and hence was renamed MCUR1
  [[cite:PUB00097799],[cite:PUB00076354],[cite:PUB00097801]]. A study in mammals and in yeast homologue
  fmp32 has reported that MCUR1 is a cytochrome c oxidase assembly factor and that it has an indirect
  role as a regulator of MCU [[cite:PUB00075452]], however, subsequent publications confirmed the function
  of MCUR1 as a regulator of MCU [[cite:PUB00097799],[cite:PUB00097800]]. The role of CCDC90B proteins
  is still not known.