id: Pfam:PF07853
pfam_id: PF07853
name: Domain of unknown function (DUF1648)
short_name: DUF1648
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF07853
counters:
  proteins: 4912
  matches: 4912
  proteomes: 4034
  taxa: 6352
  structures: 0
  alphafold_models: 3097
  domain_architectures: 19
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR012867
description: This domain is found in proteins expressed by bacterial or archaeal species. Some of these
  are annotated as being transmembrane proteins, and in fact many of these sequences contain a high proportion
  of hydrophobic residues. One protein containing this domain is immunity protein SdpI (swiss:O32241)
  from Bacillus subtilis, which provides protection for the cell against the toxic effects of its own
  SdpC killing factor, and also functions as a receptor/signal transduction protein [[cite:PUB00055038]].