id: Pfam:PF08007
pfam_id: PF08007
name: JmjC domain
short_name: JmjC_2
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF08007
counters:
  proteins: 10353
  matches: 10424
  proteomes: 7434
  taxa: 13149
  structures: 22
  alphafold_models: 7020
  domain_architectures: 139
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR003347
description: This entry includes proteins with a JmjC domain that belong to the cupin superfamily, including
  Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [[cite:PUB00090402]], Ribosomal
  oxygenase 1/2 [[cite:PUB00090403],[cite:PUB00090404]], and 50S ribosomal protein L16 3-hydroxylase from
  Escherichia coli [[cite:PUB00090405],[cite:PUB00099121]]. Proteins are bifunctional, acting as histone
  lysine demethylases and ribosomal histidine hydroxylases.