id: Pfam:PF08014
pfam_id: PF08014
name: Microtubule-associated tyrosine carboxypeptidase
short_name: MATCAP
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF08014
counters:
  proteins: 3624
  matches: 3624
  proteomes: 2517
  taxa: 4776
  structures: 3
  alphafold_models: 2518
  domain_architectures: 15
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR012548
description: This entry includes microtubule-associated tyrosine carboxypeptidases, proteins that remove
  the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function
  [[cite:PUB00101358]]. They are also able to remove the C-terminal phenylalanine residue of alpha-tubulin
  TUBA8 [[cite:PUB00101358]]. These proteins recognise adjacent tubulin dimers along the same protofilament
  [[cite:PUB00101358]].