id: Pfam:PF08350
pfam_id: PF08350
name: Methanogenesis regulatory protein FilR1, middle domain
short_name: FilR1_middle
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF08350
counters:
  proteins: 2179
  matches: 2193
  proteomes: 403
  taxa: 674
  structures: 0
  alphafold_models: 2031
  domain_architectures: 44
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR013561
description: This archaeal domain of unknown function has been found at the middle of Methanogenesis regulatory
  protein FilR1 [[cite:PUB00091155],[cite:PUB00098067]] and at the C-terminus of archaeal proteins, including
  several transcriptional regulators of the ArsR family (see [pfam:PF01022]). FilR1 is a member of the
  two-component regulatory system FilI/FilRs which is involved in the regulation of methanogenesis.