id: Pfam:PF08401
pfam_id: PF08401
name: N-terminal domain of anti-restriction factor ArdC
short_name: ArdcN
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF08401
counters:
  proteins: 6492
  matches: 6494
  proteomes: 4027
  taxa: 6807
  structures: 2
  alphafold_models: 4276
  domain_architectures: 194
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR013610
description: This is the ssDNA binding domain of anti-restriction factor ArdC deployed by plasmids and
  phages in polyvalent proteins related to the BHD domains of XPC/Rad4 and the Tc-38 domain found in kinetoplastid
  minicircle binding proteins [[cite:PUB00098071],[cite:PUB00091133],[cite:PUB00098072]]. The structure
  of this domain is composed of three alpha-helices and a three-stranded beta-sheet that supports a long
  and protuberant beta-hairpin [[cite:PUB00098072]]. This domain is also found in the N-terminal region
  of the RP4 TraC1 primase [[cite:PUB00043496]], together with the Toprim domain (pfam:PF01751, pfam:PF13362
  and pfam:PF13662).