id: Pfam:PF08574
pfam_id: PF08574
name: Transcription factor Iwr1
short_name: Iwr1
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF08574
counters:
  proteins: 3272
  matches: 3273
  proteomes: 2883
  taxa: 7650
  structures: 0
  alphafold_models: 2793
  domain_architectures: 40
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR013883
description: Iwr1 is involved in transcription from polymerase II promoters; it interacts with with most
  of the polymerase II subunits [[cite:PUB00054162]]. Deletion of this protein results in hypersensitivity
  to the K1 killer toxin [[cite:PUB00033286]].