id: Pfam:PF08583
pfam_id: PF08583
name: Cytochrome c oxidase biogenesis protein Cmc1 like
short_name: Cmc1
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF08583
counters:
  proteins: 6753
  matches: 6771
  proteomes: 3205
  taxa: 8526
  structures: 3
  alphafold_models: 5817
  domain_architectures: 81
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR013892
description: Cmc1 is a metallo-chaperone like protein which is known to localise to the inner mitochondrial
  membrane in Saccharomyces cerevisiae. It is essential for full expression of cytochrome c oxidase and
  respiration [[cite:PUB00044676]]. Cmc1 contains two Cx9C motifs and is able to bind copper(I). Cmc1
  is thought to play a role in mitochondrial copper trafficking and transfer to cytochrome c oxidase [[cite:PUB00044676]].