id: Pfam:PF08681
pfam_id: PF08681
name: Antitoxin TacA 1-like
short_name: TacA1
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF08681
counters:
  proteins: 4037
  matches: 4038
  proteomes: 2654
  taxa: 4728
  structures: 14
  alphafold_models: 2682
  domain_architectures: 9
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR014795
description: This protein family includes Antitoxin TacA 1 from Salmonella typhimurium and similar short
  sequences mainly found in bacteria. TacA1, the antitoxin component of a type II toxin -antitoxin (TA)
  system, counteracts the toxic effect of cognate toxin TacT1. TacT1 is active in complex with its antitoxin,
  acetylation of this antitoxin upregulates the acetylation of tRNAs by TacT1 [[cite:PUB00158919],[cite:PUB00158918]].