id: Pfam:PF08924
pfam_id: PF08924
name: Rv2525c-like, glycoside hydrolase-like domain
short_name: Rv2525c_GlyHyd-like
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF08924
counters:
  proteins: 3876
  matches: 3876
  proteomes: 2610
  taxa: 3609
  structures: 5
  alphafold_models: 2197
  domain_architectures: 98
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR015020
description: This domain is found in uncharacterised bacterial proteins, including the putative peptidoglycan
  hydrolase Rv2525c from Mycobacterium tuberculosis [[cite:PUB00100887],[cite:PUB00100886]]. It has been
  proposed to function as a peptidoglycan hydrolase with glycosidase activity regarding structural studies
  showed that this domain has a typical TIM-barrel-like fold, characteristic of glycoside hydrolases [[cite:PUB00100887]].
  However, it displays esterase activity toward p-nitrophenyl esters of various acyl chain length in vitro
  [[cite:PUB00100886]].