id: Pfam:PF08983
pfam_id: PF08983
name: Vasopressin V1 receptor, C-terminal
short_name: V1R_C
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF08983
counters:
  proteins: 974
  matches: 974
  proteomes: 595
  taxa: 1980
  structures: 5
  alphafold_models: 857
  domain_architectures: 3
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR015076
description: This is the conserved C-terminal domain of Vasopressin V1a/b receptors (V1R), which is involved
  in receptor trafficking and facilitates the interaction between the intracellular loops of the receptor,
  the G proteins and coupling to phospholipase C [[cite:PUB00038629],[cite:PUB00098105]]. This domain
  is unstructured and may reflect its conformational plasticity that may be necessary for proper function
  of V1R [[cite:PUB00038629]].