id: Pfam:PF09002
pfam_id: PF09002
name: Card1-like, endonuclease domain
short_name: Card1_endonuc
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF09002
counters:
  proteins: 627
  matches: 627
  proteomes: 597
  taxa: 1248
  structures: 8
  alphafold_models: 429
  domain_architectures: 7
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR015093
description: This is the endonuclease domain found in a set of bacterial proteins, including Card1 (cyclic-oligoadenylate-activated
  single-stranded ribonuclease and single-stranded deoxyribonuclease 1) from Treponema succinifaciens
  ([swissprot:F2NWD3]), a protein that is part of type III CRISPR-Cas immune response system. This protein
  consists of a CARF (CRISPR-associated Rossman fold) domain at the N-terminal, an helical hinge domain
  and a C-terminal endonuclease domain [[cite:PUB00153094]].