id: Pfam:PF09011
pfam_id: PF09011
name: HMG-box domain
short_name: HMG_box_2
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF09011
counters:
  proteins: 11264
  matches: 11403
  proteomes: 2442
  taxa: 7266
  structures: 45
  alphafold_models: 9007
  domain_architectures: 287
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR009071
description: 'This short 71 residue domain is an HMG-box domain. HMG-box domains mediate re-modelling
  of chromatin-structure. Mammalian HMG-box proteins are of two types: those that are non-sequence-specific
  DNA-binding proteins with two HMG-box domains and a long highly acidic C-tail; and a diverse group of
  sequence-specific transcription factor-proteins with either a single HMG-box or up to six copies, and
  no acidic C-tail [[cite:PUB00109134]].'