id: Pfam:PF09147
pfam_id: PF09147
name: Carbapenam-3-carboxylate synthase, N-terminal
short_name: CarA_N
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF09147
counters:
  proteins: 40
  matches: 40
  proteomes: 38
  taxa: 86
  structures: 2
  alphafold_models: 28
  domain_architectures: 2
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR015230
description: This domain is found in the N-terminal of carbapenam-3-carboxylate synthase (carA), and is
  composed of two antiparallel six-stranded beta-sheets that form a sandwich, flanked on each side by
  two alpha-helices [[cite:PUB00022497]]. carA is involved in the biosynthesis of carbapenam-3-carboxylate,
  a beta-lactam antibiotic of the carbapenem class. It catalyses the ATP-dependent formation of (3S,5S)-carbapenam-3-carboxylate
  from (2S,5S)-5-carboxymethylproline [[cite:PUB00069787],[cite:PUB00069788],[cite:PUB00069789]].