id: Pfam:PF09342
pfam_id: PF09342
name: Nudel, serine protease domain
short_name: Nudel
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF09342
counters:
  proteins: 358
  matches: 362
  proteomes: 298
  taxa: 1160
  structures: 0
  alphafold_models: 91
  domain_architectures: 64
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR015420
description: This domain is found in Nudel from Drosophila melanogaster and related proteins. Nudel is
  involved in defining embryonic dorsoventral polarity. Three proteiases ndl, gd and snk process easter
  to create active easter. Active easter defines cell identities along the dorsal-ventral continuum by
  activating the spz ligand for the Tl receptor in the ventral region of the embryo. Nudel, pipe and windbeutel
  together trigger the protease cascade within the extraembryonic perivitelline compartment which induces
  dorsoventral polarity of the Drosophila embryo [[cite:PUB00054161]].