id: Pfam:PF09345
pfam_id: PF09345
name: SiaC family regulatory phosphoprotein
short_name: SiaC
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF09345
counters:
  proteins: 1367
  matches: 1368
  proteomes: 970
  taxa: 1698
  structures: 4
  alphafold_models: 984
  domain_architectures: 5
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR018530
description: This entry represents the SiaC family regulatory phosphoprotein which undergoes a regulatory
  phosphorylation at Thr-68 of founder protein PA0170 from Pseudomonas aeruginosa, but in more distant
  homologs, T can be S. Also, it is part of motif NTSS, so may contain more than one phosphorylation site.
  Phosphorylation causes regulatory change to protein-protein interaction, in a pathway that seems broadly
  distributed, involves a diguanylate cyclase, and in the case of Pseudomonas aeruginosa affects aggregation
  and biofilm formation responses.