id: Pfam:PF09493
pfam_id: PF09493
name: Tryptophan-rich protein (DUF2389)
short_name: DUF2389
seed_status: KNOWN_HISTORICAL_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF09493
counters:
  proteins: 1174
  matches: 1174
  proteomes: 1152
  taxa: 2018
  structures: 0
  alphafold_models: 695
  domain_architectures: 3
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR012663
description: Members of this family are small hypothetical proteins of 60 to 100 residues from Cyanobacteria
  and some Proteobacteria. Prochlorococcus marinus strains have two members, other species one only. Interestingly,
  of the eight most conserved residues, four are aromatic and three are invariant tryptophans. It appears
  all species that encode this protein can synthesise tryptophan de novo.