id: Pfam:PF09807
pfam_id: PF09807
name: Elongation complex protein 6
short_name: ELP6
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF09807
counters:
  proteins: 2538
  matches: 2678
  proteomes: 2067
  taxa: 6120
  structures: 0
  alphafold_models: 2160
  domain_architectures: 48
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR018627
description: ELP6 is a subunit of the RNA polymerase II elongator complex. The Elongator complex promotes
  RNA-polymerase II transcript elongation through histone acetylation in the nucleus and tRNA modification
  in the cytoplasm. ELP5 and ELP6 play a major role in the migration, invasion and tumorigenicity of melanoma
  cells, as integral subunits of Elongator [[cite:PUB00075653]]