id: Pfam:PF09817
pfam_id: PF09817
name: RZZ complex, subunit zwilch
short_name: Zwilch
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF09817
counters:
  proteins: 1533
  matches: 1618
  proteomes: 1131
  taxa: 3705
  structures: 2
  alphafold_models: 1347
  domain_architectures: 30
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR018630
description: The protein Zwilch is an essential component of the mitotic checkpoint, which prevents cells
  from prematurely exiting mitosis. It is required for the assembly of the dynein-dynactin, Mad2 complexes
  and spindly/CG15415 onto kinetochores [[cite:PUB00054075],[cite:PUB00054076],[cite:PUB00044111]].