id: Pfam:PF09847
pfam_id: PF09847
name: Membrane protein of 12 TMs
short_name: 12TM_1
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF09847
counters:
  proteins: 429
  matches: 429
  proteomes: 404
  taxa: 835
  structures: 0
  alphafold_models: 313
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR018646
description: 'This family carries twelve transmembrane regions. It does not have any characteristic nucleotide-binding-domains
  of the GxSGSGKST type. so it may not be an ATP-binding cassette transporter. However, it may well be
  a transporter of some description. ABC transporters always have two nucleotide binding domains; this
  has two unusual conserved sequence-motifs: ''KDhKxhhR'' and ''LxxLP''.'