id: Pfam:PF10069
pfam_id: PF10069
name: Sensory domain in DIguanylate Cyclases and Two-component system
short_name: DICT
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10069
counters:
  proteins: 1776
  matches: 1776
  proteomes: 1020
  taxa: 1804
  structures: 0
  alphafold_models: 1244
  domain_architectures: 30
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR019278
description: 'DICT is a sensory domain found associated with GGDEF, EAL, HD-GYP, STAS, and two component
  systems (histidine-kinase type). It assumes an alpha+beta fold with a 4-stranded beta-sheet and might
  have a role in light response (Natural history of sensor domains in bacterial signaling systems by Aravind
  L, LM Iyer, Anantharaman V, from ''Sensory Mechanisms in Bacteria: Molecular Aspects of Signal Recognition.''
  Caister Academic Press. 2010) - see (http://de.scribd.com/doc/28576661/Bacterial-Signaling-Chapter)'