id: Pfam:PF10070
pfam_id: PF10070
name: Probable inorganic carbon transporter subunit DabA
short_name: DabA
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10070
counters:
  proteins: 2360
  matches: 2419
  proteomes: 2033
  taxa: 3561
  structures: 3
  alphafold_models: 1624
  domain_architectures: 7
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR018752
description: This entry represents the probable inorganic carbon transporter subunit DabA, which is part
  of an energy-coupled inorganic carbon pump together with DabB subunit in DAB operons (DAB1 and DAB2),
  found in a wide range of bacteria and archaea. Members of this family were previously known as UPF0753.
  DAB operon is required for CO2 concentrating mechanisms [[cite:PUB00093673]]. The substrate of this
  subunit may be CO2 rather than carbonate ions based on kinetic calculations and in experimental assays
  in which E.coli was deleted of its carbonic anhydrase genes and expression of DAB2 operon restores its
  growth. Structural homology modelling suggests that DabA contains a domain that is distantly homologous
  to a type II beta-carbonic anhydrase (CA).