id: Pfam:PF10154
pfam_id: PF10154
name: Ferry endosomal RAB5 effector complex subunit 3
short_name: Fy-3
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10154
counters:
  proteins: 1971
  matches: 2297
  proteomes: 1364
  taxa: 4364
  structures: 0
  alphafold_models: 1732
  domain_architectures: 44
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR019311
description: This entry represents a human Ferry endosomal RAB5 effector complex subunit 3 (Fy-3) and
  similar sequences from animals and some fungal species. Fy-3 is a component of the FERRY complex (Five-subunit
  Endosomal Rab5 and RNA/ribosome intermediary), which is involved in the localisation and the distribution
  of specific mRNAs most likely by mediating their endosomal transport. The complex recruits mRNAs and
  ribosomes to early endosomes through direct mRNA-interaction [[cite:PUB00152264]].