id: Pfam:PF10156
pfam_id: PF10156
name: Subunit 17 of Mediator complex
short_name: Med17
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10156
counters:
  proteins: 2870
  matches: 2912
  proteomes: 2346
  taxa: 6182
  structures: 33
  alphafold_models: 2445
  domain_architectures: 41
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR063477
description: This Mediator complex subunit was formerly known as Srb4 in yeasts or Trap80 in Drosophila
  and human. The Med17 subunit is located within the head domain and is essential for cell viability to
  the extent that a mutant strain of cerevisiae lacking it shows all RNA polymerase II-dependent transcription
  ceasing at non-permissive temperatures.