id: Pfam:PF10226
pfam_id: PF10226
name: CCDC85 family
short_name: CCDC85
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10226
counters:
  proteins: 3544
  matches: 3556
  proteomes: 1178
  taxa: 3878
  structures: 0
  alphafold_models: 3112
  domain_architectures: 28
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR019359
description: This entry includes human CCDC85A/B/C and C. elegans Picc-1 protein. Picc-1 serves as a linker
  protein which helps to recruit the Rho GTPase-activating protein, pac-1, to adherens junctions [[cite:PUB00078905]].
  Human CCDC85B suppresses the beta-catenin activity in a p53-dependent manner [[cite:PUB00078906]].