id: Pfam:PF10307
pfam_id: PF10307
name: HAD domain family 1 in Swiss Army Knife RNA repair proteins
short_name: HAD_SAK_1
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10307
counters:
  proteins: 1186
  matches: 1192
  proteomes: 1103
  taxa: 2287
  structures: 0
  alphafold_models: 991
  domain_architectures: 24
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR018812
description: Family of HAD domain phophoesterases observed in large eukaryotic proteins with predicted
  role in RNA repair, the so-called 'Swiss Army Knife' repair proteins. May be involved in phosphate group
  removal during RNA re-ligation [[cite:PUB00091037]].There are two characteristic sequence motifs, GGWW
  and TGR.