id: Pfam:PF10507
pfam_id: PF10507
name: Transmembrane protein 65
short_name: TMEM65
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10507
counters:
  proteins: 2227
  matches: 2244
  proteomes: 1373
  taxa: 4345
  structures: 0
  alphafold_models: 1946
  domain_architectures: 57
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR019537
description: MEM65 is an intercalated disc protein that interacts with with connexin 43 (Cx43) and is
  required for correct localization of Cx43 to the intercalated disc. It is essential for cardiac function
  in zebrafish [[cite:PUB00078902]].