id: Pfam:PF10753
pfam_id: PF10753
name: Toxin GhoT_OrtT
short_name: Toxin_GhoT_OrtT
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10753
counters:
  proteins: 370
  matches: 370
  proteomes: 339
  taxa: 502
  structures: 0
  alphafold_models: 226
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR019689
description: GhoT is part of the GhoT-GhoS type V toxin-antitoxin (TA) system [[cite:PUB00065335],[cite:PUB00074308]].
  OrtT is homologous to GhoT, but it is not part of a TA pair. In this case, it acts as an independent
  toxin to reduce growth during stress related to amino acid and DNA synthesis [[cite:PUB00074307]].