id: Pfam:PF10771
pfam_id: PF10771
name: Winged helix-turn-helix domain (DUF2582)
short_name: DUF2582
seed_status: KNOWN_HISTORICAL_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10771
counters:
  proteins: 575
  matches: 575
  proteomes: 323
  taxa: 576
  structures: 2
  alphafold_models: 404
  domain_architectures: 4
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR019707
description: This family is conserved in bacteria and archaea. The function is not known. The structure
  of two proteins in this family were solved using NMR and shown to adopt a winged helix-turn-helix fold
  [[cite:PUB00075673]]. Structural analysis shows that these proteins form an unusual dimeric conformation.
  This dimer was shown to be similar to that found in the FadR and TubR wHTH domains. It was suggested
  [[cite:PUB00075673]] that these proteins are not very likely to bind to DNA.