id: Pfam:PF10869
pfam_id: PF10869
name: Domain of unknown function (DUF2666)
short_name: DUF2666
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10869
counters:
  proteins: 54
  matches: 85
  proteomes: 54
  taxa: 113
  structures: 1
  alphafold_models: 52
  domain_architectures: 3
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR022620
description: This domain found in archaeal proteins, including PF2050 from Pyrococcus furiosus ([swissprot:Q8TZE5]).
  PF2050, with an overall globular structure, contain this domain twice, each showing an antiparallel
  beta-sheet and an alpha-helical bundle, and shows a positively charged basic cleft on one side. This
  protein interacts with circular and linear dsDNA [[cite:PUB00100885]].