id: Pfam:PF10899
pfam_id: PF10899
name: Putative abortive phage resistance protein AbiGi, antitoxin
short_name: AbiGi
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10899
counters:
  proteins: 323
  matches: 323
  proteomes: 317
  taxa: 774
  structures: 0
  alphafold_models: 208
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR021223
description: This is a bacterial family of proteins with unknown function. AbiGi is a family of putative
  type IV toxin-antitoxin system antitoxins. The AbiG abortive phage resistance system affects lactococcal
  bacteriophages phiP335 and phiQ30 but not the other P335 phage species. AbiGii toxin appears to confer
  resistance to phages by a mechanism of abortive infection that acts by interfering with phage RNA synthesis
  [[cite:PUB00016885]]. The cognate toxin is found in [pfam:PF16873].