id: Pfam:PF10908
pfam_id: PF10908
name: Tlde1 domain
short_name: Tlde1_dom
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10908
counters:
  proteins: 1639
  matches: 1640
  proteomes: 1100
  taxa: 1688
  structures: 0
  alphafold_models: 956
  domain_architectures: 18
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR021225
description: This domain is found in Tlde1 family of antibacterial effectors secreted by the type VI secretion
  system (T6SS). Tlde1 family is evolutionarily related to l,d transpeptidases which form mDAP3-mDAP3
  peptidoglycan crosslinks. Tlde1 family is widespread among Proteobacteria and is divided into three
  subfamilies (Tlde1a, Tlde1b and Tlde1c) [[cite:PUB00100165]].