id: Pfam:PF10923
pfam_id: PF10923
name: BREX system ATP-binding protein BrxC/D
short_name: BrxC_BrxD
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10923
counters:
  proteins: 2010
  matches: 2091
  proteomes: 1770
  taxa: 3346
  structures: 0
  alphafold_models: 1261
  domain_architectures: 23
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR021228
description: This is the ATP-binding domain found in proteins that are associated with Bacteriophage Exclusion
  (BREX) system, a defense system that allows bacteriophage adsorption but blocks phage DNA replication
  [[cite:PUB00093365]]. This domain is found in the ATP-binding proteins BrxC/pglY (due to its homology
  with pglY from Pgl system) and BrxD [[cite:PUB00093365]].