id: Pfam:PF11125
pfam_id: PF11125
name: Bacteriophage MS2, lysis protein
short_name: Phage_MS2_lysis
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11125
counters:
  proteins: 23
  matches: 23
  proteomes: 2
  taxa: 22
  structures: 0
  alphafold_models: 1
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR022599
description: This entry represents putative lysis proteins from Bacteriophage MS2 and Bacteriophage BZ13.
  The bacteriophage MS2 lysin protein swiss:C0M1L5 was identified as an overlapping cistron in the bacteriophage
  MS2 RNA [[cite:PUB00053761]]. This proteins induces the formation of specific membrane adhesion sites
  between the inner and outer membranes, apparently leading to host cell lysis. Lysis may be performed
  via activation of host murein hydrolases [[cite:PUB00097482],[cite:PUB00097483]].