id: Pfam:PF11127
pfam_id: PF11127
name: Inner membrane protein YgaP-like, transmembrane domain
short_name: YgaP-like_TM
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11127
counters:
  proteins: 11110
  matches: 11132
  proteomes: 7897
  taxa: 11931
  structures: 1
  alphafold_models: 7483
  domain_architectures: 25
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR021309
description: 'This domain is found in proteins from bacteria and archaea, including Inner membrane protein
  YgaP from Escherichia coli, a membrane protein with a rhodanese domain (Pfam: PF00581) that may have
  sulfurtransferase activity. YgaP adopts a dimeric assembly. This entry represents the transmembrane
  domain. It consist of two slightly tilted alpha-helices [[cite:PUB00100968]]. Structure prediction suggests
  that this region may homodimerise to form a 4 helical bundle.'
