id: Pfam:PF11139
pfam_id: PF11139
name: Sap, sulfolipid-1-addressing protein
short_name: SfLAP
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11139
counters:
  proteins: 3664
  matches: 3667
  proteomes: 2162
  taxa: 2950
  structures: 0
  alphafold_models: 2255
  domain_architectures: 9
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR021315
description: SAP is a transmembrane transport protein with six predicted transmembrane helices, with a
  hydrophilic domain between helices 3 and 4. This hyrodphobic region is highly variable among identified
  Gap-like (GPL, peptidoglycolipid, addressing protein) proteins and may be involved in substrate recognition.
  SAP also belongs to the LysE protein superfamily ([pfam:PF01810]), whose members have been implicated
  in small molecule transport in bacteria. Other Gap proteins export metabolites across the cell membrane
  so it is possible that Sap specifically may be involved in transport of sulfolipid-1 across the membrane
  [[cite:PUB00077558]].