id: Pfam:PF11203
pfam_id: PF11203
name: Putative type VII ESX secretion system translocon, EccE
short_name: EccE
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11203
counters:
  proteins: 2862
  matches: 2862
  proteomes: 1756
  taxa: 2078
  structures: 7
  alphafold_models: 1681
  domain_architectures: 4
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR050051
description: EccE is a family of largely Gram-positive bacterial transmembrane componenets of the type
  VII secretion system characterised in Mycobacterium tuberculosis, systems ESX1-5. Translocation of virulent
  peptides through the membranes is thought to be mediated via a complex that includes EccB, EccC, EccD,
  EccE, and MycP [[cite:PUB00083129],[cite:PUB00106938]]. EccB, EccC, EccD, and EccE form a stable complex
  in the mycobacterial cell envelope [[cite:PUB00083131]].