id: Pfam:PF11251
pfam_id: PF11251
name: HamA Heme-Oxygenase-like enzyme family
short_name: HamA_HO-like
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11251
counters:
  proteins: 1871
  matches: 1873
  proteomes: 1805
  taxa: 2600
  structures: 1
  alphafold_models: 1169
  domain_architectures: 5
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR024423
description: This entry, previously known as DUF3050, represents HamA, the key enzyme responsible for
  forming the nitrogen-nitrogen bond in the diazeniumdiolate moiety of fungicide fragin [[cite:PUB00163876]].
  HamA adopts a heme oxygenase-like fold, forming a hydrophobic cavity within a helical bundle that likely
  accommodates the substrate [[cite:PUB00163876]].