id: Pfam:PF11394
pfam_id: PF11394
name: Type VI lipase adapter protein Tla3, N-terminal
short_name: Tla3_N
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11394
counters:
  proteins: 218
  matches: 218
  proteomes: 128
  taxa: 209
  structures: 1
  alphafold_models: 126
  domain_architectures: 3
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR021531
description: This entry represents the N-terminal domain of Type VI lipase adapter protein Tla3, an adapter
  protein that targets and loads the Tle3 toxin onto the H2 type VI secretion system (H2-T6SS) machinery
  through an interaction with the TTR domain of VgrG2b [[cite:PUB00100136]] and it seems specific for
  Tle3 [[cite:PUB00100136]]. This domain and its C-terminal ([pfam:PF20995]) are both required for the
  interaction with the toxin [[cite:PUB00100136]].