id: Pfam:PF11681
pfam_id: PF11681
name: Bacteriophage PhiTE tail tube protein
short_name: Phage_Tube_PhiTE
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11681
counters:
  proteins: 636
  matches: 636
  proteomes: 594
  taxa: 1273
  structures: 10
  alphafold_models: 225
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR021695
description: This entry includes the tail tube protein of bacteriophage PhiTE that infects the plant pathogen
  Pectobacterium atrosepticum. The tube protein forms the rigid inner tube of the phage tail and consists
  of a primary eight-stranded beta-sandwich flanked by a large alpha-helix. The luminal components of
  each tube protein's beta-sandwich intercalate with adjacent tube proteins in the hexameric disk to form
  a continuous 24-stranded beta-barrel on the internal surface of each ring. The inner tube lumen has
  a strong negative charge distribution, typical of bacteriophage DNA conduits. An extended beta-hairpin
  motif extends between strands 2 and 5 of the beta-sandwich and wraps around the tube, making contacts
  with loops from head distal tube subunits. The C-terminal arm features a second alpha-helix that wraps
  laterally around adjacent subunits and forms strong hydrophobic contacts with helices from the sheath
  D1 domain.